Opioids bind to specific receptors in the brain that reduce the transmission of pain signals throughout the body. Opioids include:
- prescription pain medications like:
- hydrocodone (Vicodin)
- hydromorphone (Dilaudid)
- meperidine (Demerol)
- morphine (MS Contin)
- oxycodone (OxyContin, Percocet)
For a complete list of prescription opioids, see WebMD Guide to Narcotic Pain Medications.
When there is too much opioid in the body, a person can lose consciousness and stop breathing – this is an overdose. An opioid overdose can happen suddenly or come on slowly over a few hours. Without oxygen, a person can die.
Risks for an opioid overdose include:
- Using opioids again after your tolerance has dropped (e.g., like after being in treatment, a hospital, or jail). After a break from opioids, the body can’t handle as much as it did before.
- Taking prescription pain medication more often or in higher doses than prescribed-or using someone else’s prescription pain medication. The dose could be too much.
- Using heroin or pills bought on the street. Heroin and street pills often contain other substances that can be dangerously toxic.
- Using opioids with alcohol or other drugs including sleeping pills, benzodiazepines (“benzos” like Valium and Xanax), cocaine and methamphetamine.
- Any current or chronic illness that weakens the heart or makes it harder to breathe.
- Using opioids alone. You are more likely to die from an overdose if no one is there to help.
- Previous overdose. A person who has overdosed before is more likely to overdose again.
What to do in an opioid overdose
Minutes count in an opioid overdose. If you think someone has overdosed, follow these steps:
Check for signs of overdose.
- Won’t wake up. Try rubbing your knuckles hard on their sternum.
- Slow or no breathing
- Pale, ashy, cool skin
- Blue or gray lips or fingernails
Tell the dispatcher where you are and that someone is not breathing or is unconscious.
If you are trying to help in an overdose, WA State’s 911 Good Samaritan/Overdose Law protects both you and the overdose victim from drug possession charges. Don’t be afraid to call 911 for help!
If you can’t stay until 911 help arrives, place the person on their side and where first responders can find them.
Give naloxone and rescue breaths.
- Tilt head back. Lift chin. Pinch nose.
- Give a full breath. Their chest should rise when you exhale.
- Give a breath every 5 seconds.
If you have naloxone, give one dose. Naloxone can take 2-3 minutes to work, so start giving rescue breaths. If the person is still not breathing after 2-3 minutes, give a second dose of naloxone. Continue rescue breathes until the person wakes up or medical help arrives.
If the person wakes up and starts breathing, stay with them. Encourage them to get follow-up medical care.
When the naloxone wears off in 30-90 minutes, the person could stop breathing again. Encourage the person to be taken to a clinic or emergency room where health care staff can:
- Monitor their breathing.
- Manage any withdrawal symptoms.
- Treat any other medical conditions.
Click on an image or link below to learn how to use that type of Naloxone:
WA State Overdose Prevention & Response
This training video covers overdose risks, the WA State Good Samaritan Law and shows a step-by-step demonstration on what to do in an opioid overdose (including rescue breathing and naloxone). It depicts drug paraphernalia and reenacts an overdose.
Download a Copy
Right-click and save one of these links to download a copy of this video (mp4 format):
English without captions | English with captions | Spanish without captions
This brochure provides information about opioids, overdose risks, and what to do if someone is overdosing.
Available in multiple languages: English, Amharic, Arabic, Chinese, Farsi, French, Hindi, Japanese, Khmer / Cambodian, K’iche, Korean, Laotian, Marshallese, Oromo, Punjabi, Russian, Samoan, Somali, Spanish, Tagalog, Tigrinya, Ukrainian, and Vietnamese.
Request hard copies of this brochure and many others through the ADAI Clearinghouse.
Thank you to King County Department of Community and Human Services-Behavioral Health and Recovery Division for the translations! Support for this project was through a federal grant via the Washington State Health Care Authority, specifically the Washington State Opioid Response (SOR) Grant.
- Watch an overdose training video.
Find several training videos, including the WA State Overdose Prevention and Relapse training for general audiences and trainings specifically for community health workers and pain patients (and their friends/family). You’ll also find our Preventing Opioid Overdose training tool, an interactive video that teaches you how to recognize and respond to an overdose.
- Naloxone Instructions from WA State Department of Health (available in English, Spanish, Chinese, Russian, Ukrainian, and Vietnamese).
- Download the handout You survived an overdose. Here’s what to do next. This handout provides information for people who use heroin about steps to take after an overdose. When printing this pdf, select “actual size.”
For service providers and first responders
- First Responders Can Safely Administer Naloxone during the COVID-19 Pandemic from Department of Health and Human Services
- Overdose Prevention and Response from Public Health-Seattle & King County: quick tips for service providers to reduce the risks to their clients who use drugs.